IBC 2008 Scientific Programme

Disclaimer: This is the Final Programme, as at 20 June 2008.

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Monday, 14 July 2008

Opening Plenary 2a: Opening Session
O'Reilly Hall
Chair: Thomas Louis, Johns Hopkins Bloomberg SPH, United States
Welcome to the IBC on behalf of the IBS (Tom Louis)

Welcome to the IBC on behalf of the IBC British and Irish Region (David Balding)

Welcome to the IBC on behalf of the LOC (John Hinde)

Welcome to UCD, Dublin and Ireland (including Dr Hugh Brady (UCD President))

Introduction to the Conference Scientific Programme (Jean-Louis Foulley)

Presidential Address: Biometry and the IBS - Strength through diversity (Andrew Mead)

Conference Notices/Housekeeping Announcements (John Hinde)

Coffee Break
Session 3a: Invited Session: Using maps to depict relationships between variables
Chair: Linda Young, University of Florida, United States
Session Organiser: Linda Young

Introduction (Linda Young)

Linking Environmental Data and Health Data from Different Spatial Scales: A Case Study from Florida’s Environmental Public Health Tracking Initiative
Carol Gotway Crawford , Centers for Disease Control and Prevention, United States

Inferential Maps for Spatial and Spatio-temporal Data
Peter John Diggle, Lancaster University, United Kingdom

Surveillance to Detect Emerging Space-time Clusters
Renato Assuncao, UFMG - Brazil, Brazil

Discussion and General Conclusions (Linda Young)

Session 3b: Invited Session: Statistical methods in mental health research
Chair: Ralitza Gueorguieva, Yale University, United States
Session Organisers: Ralitza Gueorguieva and Tom Ten Have

Exploratory Multidimensional Methods in the Analysis of Psychiatric Data
Bruno Falissard, Université Paris Sud, France

Modeling Diffusion and Effects of New Drugs: Methods and Applications
Sharon-Lise Normand, Harvard Medical School, United States

Clustering and Partitioning of Functional Data for Understanding the Heterogeneity in Psychiatric Diagnosis
Eva Petkova, New York University, United States

Discussant (Haiqun Lin)

General Conclusions (Ralitza Gueorguieva)

Session 3c: Analysis of Genetic Data I
Identifying Common Quantitative Trait Loci For A Bivariate Phenotype
Saurabh Ghosh, Indian Statistical Institute, India

On the Theory of QTL Detection
Charles-Elie Rabier, INRA SAGA Toulouse, France

Bayesian Analysis of Complex Traits in Multiple Related Plant Populations
Marco Bink, Plant Research International b.v., Netherlands

The Quality of Genetic Linkage Maps
Johannes Jansen, Wageningen University and Research Centre, Netherlands

Rank-based Model Selection in Locating Multiple Interacting QTL
Malgorzata Zak, Wroclaw University of Technology, Poland

A Latent Variable Approach to Multivariate Quantitative Trait Loci
Bob O'Hara, University of Helsinki, Finland

Session 3d: Bayesian methods in Medical Research I
Using Value of Information Methodology to Determine the Sample Size for a Randomized Clinical Trial from an Industry Perspective
Andrew Willan, SickKids Research Institute, Canada

Bayesian Approach to Clinical Trials with Dichotomous Outcomes
Boris Zaslavsky, FDA, United States

A Bayesian Approach for Inference from a Bridging Study with Binary Outcomes
Debjit Biswas, Bristol-Myers Squibb Company, India

Bayesian Semiparametric Modelling of Univariate and Bbivariate Longitudinal Data
John Tendekai Maringwa, Center for Statistics, University of Hasselt, Belgium

Implications of Using Different Types of Priors in a Three-level Hierarchical Bayesian Model for the Analysis of Drug Adverse Events
David Prieto-Merino, LSHTM, United Kingdom

A Bayesian Method for Cross-Trial Inference in the Non-Inferiority Setting
Siobhan Everson-Stewart, University of Washington, United States

Session 3e: Experimental Design
Chair: Andrew Mead, University of Warwick, United Kingdom
Optimal Sampling for the SIS Epidemic
Daniel Pagendam, University of Queensland, Australia

Usage of Fractional Factorial Designs for Testing the Technology of Crop Production
Dariusz Zaluski, University of Warmia and Mazury, Poland

A New and Simple Method to Test Interaction in Block Design
Karl Moder, University of Natural Resources and Applied Life Sciences, Austria

Experimental Designs to Evaluate Aanalytic and Affective Attitudes in Sensory Trials
Emlyn Williams, Australian National University, Australia

Small Optimal Designs for a Simple Logistic Model with Probability Uncertainty
Ken Russell, University of Wollongong, Australia

Optimal Design of Epidemic Experiments
Alex Cook, University of Cambridge, United Kingdom

Session 3f: Ecological Data Analysis
Analysis of the Lethargic Crab Disease by a Mathematical Model
Paulo Mancera, UNESP, Brazil

Cubic Splines for Estimating the Distribution of Residence Time for Southern Right Shales in the Auckland Islands
Rachel Fewster, University of Auckland, New Zealand

Applying Genetics to Characterise the Invasion of Islands by Rats in New Zealand
Steven Miller, Trinity College Dublin, Ireland

Measuring the functional value of biodiversity in plant communities
John Connolly, UCD, Ireland

New Tools for Compositional Data Analysis of Male Preference in Fish Species
Josep Antoni Martín-Fernández, University of Girona, Spain

Modelling the Survival of Bighorn Sheep
Lauren Oliver, University of Kent, United Kingdom

UCD Restaurant
Session 4a: Invited Session: Modern challenges in hierarchical Bayesian modelling
Chair: jean-Jacques Daudin, AgroParisTech, France
Session Organisers: Brad Carlin and Eric Parent

Approximate Bayesian Inference for Latent Gaussian Models
Håvard Rue, Norwegian University of Science and Technology, Norway

Spatial Interpolation of high-frequency Monitoring Data
Michael Stein, University of Chicago, United States

Advances and Challenges in Modelling Animal Movement Data
Jay Ver Hoef, NOAA National Marine Fisheries Service, United States

Ecological issues and Hierarchical Bayes Modelling Techniques: Case Studies from Fisheries Ecology
Eric Parent, AgroParisTech/ENGREF, France

General Discussion and Conclusions (Jean-Jacques Daudin)

Session 4b: Biometry
Illustrating Marginal Structural Models by comparison of estimation methods for two different questions on breast cancer chemotherapies
Christine Gall, University of Freiburg, Germany

Design of Observational Longitudinal Studies with a Time-Varying Exposure
Xavier Basagana, Centre for Research in Environmental Epidemiology (CREAL), Spain

Forecasting the Collapse of Trees with Hollows
Jeff Wood, The Australian National University, Australia

Using Statistical Models to Identify Factors that Influence Ions formed in a Tandem Mass Spectrometer and Predict Abundance of these Ions
Sheila Barton, LSHTM and University of Southampton, United Kingdom

Statistical Analyses of Epidemics
Tom Britton, Stockholm University, Sweden

The Statistical Theory and Analysis of GMO Enforcement
Alistair Murray, Central Science Laboratory, United Kingdom

Session 4c: Epidemiological Methods I
Extension of Simple Predictive Models to Account for Regional Variation in Cancer Incidence Prediction
Tadeusz Dyba, Finnish Cancer Registry, Finland

Bayesian Partition Models for Exposure Data
Øivind Skare, Norwegian Institute of Public Health, Norway

Time to Extinction of Age-dependent Branching Processes: Application to Outbreaks of Infectious Disease
Maroussia Slavtchova-Bojkova, Sofia University, Faculty of Mathematics and Informatics, Bulgaria

Bayesian Analysis of Covariate Profiles
John Molitor, Imperial College, London, United Kingdom

Investigating Spatial Similarities in the Epidemiology of Childhood Leukaemia and Diabetes in Yorkshire, UK, using a Shared Spatial-Temporal Component Model
Samuel Manda, South African Medical Research Coucil, South Africa

Bayesian Modelling of Liver Cancer Incidence Trends based on Incidence to Mortality Rate Ratios
Ramon Cleries, Catalan Institute of Oncology, Spain

Session 4d: Models in Forestry, Fisheries and Wildlife
Semi-Markov Switching Linear Mixed Model for Analyzing Forest Tree Development
Florence Chaubert-Pereira, CIRAD, UMR DAP & INRIA, Virtual Plants team, France

Unsupervised Classification of Species Groups based on Mixture Matrix Population Models
Frédéric Mortier, CIRAD, France

A New Feature Extraction Method for Very Non-Normal Data: Analysis of Multivariate Species-size Data from Purse-seine Tuna Fisheries
Mihoko Minami, The Institute of Statistical Mathematics, Japan

Enhancing Multivariate Analyses in Forestry and Biopulping Applications with Biplot Methodology
Sugnet Lubbe, British American Tobacco, South Africa

Stochastic Spatio-temporal Modeling of Forest Dynamics
Fabien Campillo, INRIA, France

Exploring the Segmentation Space for Multiple Change-point Models
Yann Guédon, CIRAD, France

Session 4e: Correlated Data in Medical Research
Misspecified Random-effects Distribution in Generalized Linear Mixed Models: Perception and Problems
Ariel Alonso Abad, Hasselt University, Belgium

Diagnostic Tools for Misspecification in Mixed Models
Saskia Litiere, Hasselt University, Belgium

Using Earlier Measures in a Longitudinal Sequence as Potential Surrogate for a Later One
Pryseley Assam, Hasselt University, Belgium

Semiparametric ROC Models with Multiple Biomarkers
Eunhee Kim, University of North Carolina at Chapel Hill, United States

Joint Models of Longitudinal and Survival Data with both Retrospectively and Prospectively Measured Longitudinal Data
Jesse D Raffa, University of Waterloo, Canada

Measuring Uncertainty in a Predictive Model: A Case Study
Elizabeth Stojanovski, Newcastle University, Australia

Session 4f: Missing Data I
Every Missing not at Random Model has got a Missing at Random Counterpart with Equal Fit
Geert Molenberghs, Hasselt University, Belgium

Shared-parameter Models and Missingness at Random
An Creemers, University of Hasselt, Belgium

Insights into the use of Bayesian Models for Informative Missing Data
Alexina Mason, Imperial College London, United Kingdom

Learning about Missing Data in a Psychiatic Trial
Dan Jackson, MRC, United Kingdom

Nonignorable Nonresponse, Random Subsamples of Nonrespondents and How to Adjust for the Missing Data
Christiana Drake, University of California, Davis, United States

Informative Missing Data in Survival Analysis
Jane Hutton, University of Warwick, United Kingdom

Session 4g: Poster Session I: Cancer Research and Pharmaceutical Applications
U-statistics for Censored Data with Applications

Methods to Evaluate the Relationship between Survival Times
Nicolae Todor, Cancer Institute "Ion Chiricuta", Romania

Nonlinear Eelliptical Models for Correlated Data
Cibele Russo, Universidade de São Paulo, Brazil

Estimating Crude Cumulative Incidences Through Multinomial Logit Regression on Discrete Cause Specific Hazards
Federico Ambrogi, University of Milan, Italy

Repeated Measures Analysis with Measurements on Ambiguous Scales
Olena Kravchuk, University of Queeensland, Australia

Determination of an Overconsumption's Threshold for the Evaluation of Abuse and Dependence Potential of Drugs
Lise Bellanger, Université de Nantes, France

Recommendations for the Primary Analysis of Continuous Endpoints in Longitudinal Clinical Trials
Peter Lane, GlaxoSmithKline, United Kingdom

Developing a Population Predictive Model for Oesophagitis and Gastroduodenal Erosions in Subjects with Uninvestigated Dyspepsia
Graham Law, University of Leeds, United Kingdom

Omnibus Tests for Comparison of Competing Risks
Yichuan Zhao, Georgia State University, United States

Automatic Beam's Eye View
Ahmad-Saher Azizi-Sultan, King Saud University, Saudi Arabia

On Approaches for Modelling Time-Varying Effects in Survival Analysis
Anika Buchholz, University of Freiburg, Germany

Breast Cancer Screening Program: A Population Profile of Central Portugal
Bruno de Sousa, University of Minho, Portugal

Competing Risks Regression on Time-dependent Covariates for Finding Optimal Chemotherapy Dosages
Giuliana Cortese, University of padova, Italy

A Differential Equations Approach to In Vitro - In Vivo Correlation Modelling
Clare Gaynor, University College Dublin, Ireland

Latent Class Regression Analysis of Colorectal Cancer Data
Wendy Harrison, University of Leeds, United Kingdom

Graphical Methods for Detection of Outlying Observations. Application in Designs of Bioavailability Studies
Enachescu Denis, University of Bucharest, Romania

A Time Scaling Approach to Developing an In Vitro-In Vivo Correlation (IVIVC) Model Using A Convolution Based Technique
Cian Costello, University College Dublin, Ireland

Modelling the Effect of Accumulating Recurrences and Progression in Bladder Cancer Data
Cristina Santamaria, Universidad Politécnica de Valencia, Spain

Estimating the Mean Quality Adjusted Life using Aalen’s Linear Hazards Model
Vaman Jalikop, Bangalore University, India

Optimisation Using Response Surface Methodology Applied to a Pharmaceutical Plant
Sinead O'Neill, University College Cork, Ireland

Comparison of Completeness Estimates in Cancer Registration – A Simulation Sstudy
Irene Schmidtmann, Johannes Gutenberg University Mainz, Germany

Correlation between Claus, Gail and Tyrer-Cuzik Models in a Population-based Cohort Study
Aishameriane Schmidt, UFRGS, Brazil

Pharmacogenetic Pathway Analysis of Irinotecan
Gary Rosner, The University of Texas M.D. Anderson Cancer Center, United States

Statistical Validity and Power for Testing for Heterogeneous Effects with Quantitative Traits in Pharmacogenetic Studies
Todd Nick, Cincinnati Children's Hospital Medical Center, United States

Coffee Break
Session 5a: Invited Session: Mixed modelling for series of experiments in plant breeding
Chair: Hans-Peter Piepho, Universtaet Hohenheim, Germany
Session Organiser: Hans-Peter Piepho

Randomization-Derived Mixed Models for Analyzing Series of Variety Trials
Pawel Krajewski, Institute of Plant Genetics, Poland

Modeling of Genotype-to-phenotype Relations using Multi-environment Trial Data
Fred van Eeuwijk, Wageningen University, Netherlands

Extensions of AI-REML Estimation for Multi-environment Trials
Brian Cullis, Agricultural Research Institute, Australia

Discussant (Mark Cooper)

Session 5b: Special Session: UK National Centre for Statistical Ecology
Chair: Stephen Buckland, University of St Andrews, United Kingdom
Session Organisers: UK National Centre for Statistical Ecology (Steve Buckland)

Some Uses for Mixed Models in Ecology
David Elston, Biomathematics and Statistics Scotland, United Kingdom

Hierarchical Modeling of Out-migrating Juvenile Salmon Survival in an Estuary Network using Release-recovery Data
Ken Newman, US Fish and Wildlife Service, United States

Recent Developments in Statistical Ecology
Byron Morgan, University of Kent, United Kingdom


Session 5c: Regression Methods in Medical Research
Selection of Covariates for Multivariable Regression in Observational Studies: A Review
Abhik Das, RTI International, United States

Normal or Not?
Ozlem Ilk, Middle East Technical University, Turkey

A Trend Estimation from Grouped Dose-response Data and its Application to Meta-analysis
Kunihiko Takahashi, National Institute of Public Health, Japan

Detecting Drug-related Signatures in EEG Data using Model-directed Canonical Correlation Analysis
Phil Brain, Pfizer Global R & D, United Kingdom

The Fine & Gray Model for Competing Risks with Left Truncated Data or Time-dependent Covariates
Ronald Geskus, Academic Medical Center, Netherlands

Developing Risk Models for Survival Outcomes when the Number of Events is Small
Gareth Ambler, University College London, United Kingdom

Session 5d: Genomics, Proteomics, ...
An Adjusted Test Statistic based on Shrunken Sample Variance for Identifying Differentially Expressed Genes in Microarray Experiments
Akihiro Hirakawa, Pharmaceuticals and Medical Devices Agency, Japan

Testing Procedures on Comparisons of Several Treatments with one Control in a Microarray Setting
Ziv Shkedy, Hasselt University, Belgium

A Sparse Method to Handle Two High Dimensional Symetric Data Sets
Kim-Anh Lè Cao, INRA and University of Toulouse, France

Sparseness determination for boosting estimation of high-dimensional survival models
Harald Binder, University of Freiburg, Germany

A Flexible Mixture Model to Describe Multifactorial Genetic Risk Factors of Complex Disease, with an Application for Gene-gene and Gene-environment Interaction Discovery
Joanna Davies, University of Oxford, United Kingdom

The Analysis of DGGE Gels
David Baird, VSN (NZ) Limited, New Zealand

Session 5e: Functional Data Analysis and Time Series
Obtaining Improved Estimates in Time Series Studies of the Association between Particulate Matter Air Pollution and Mortality
Steven Roberts, australian national university, Australia

A Warped Failure Time Model for Human Mortality
Carlo Giovanni Camarda, Max Planck Institute for Demographic Research, Germany

An Approach to the Analysis of Spatially Correlated Multilevel Functional Data
Ana-Maria Staicu, University of Bristol, United Kingdom

Using Random Walk in Models specified by Stochastic Differential Equations to Determine the Best Expression for the Bacterial Growth Rate
Kirsten Riber Philipsen, Technical University of Denmark, Denmark

Asymmetric Least Squares Smoothing and Life Expectancy Frontiers
Sabine Schnabel, Max Planck Institute for Demographic Research, Germany

Wavelet Alternative for Solving Specific Problems in Pattern Recognition of Human Gait
Peter Amoako-Yirenkyi, Kwame Nkrumah University of Science and Technology, Ghana

Session 5f: Causal Inference in Clinical Trials
Structural Models to Characterize the Clinical Benefits of an On-demand Drug Dosing Regimen: Model Selection and Validation
Laetitia Comté, University of Liège, Belgium

Assessing Causal Effects with Truncation Due to Death and Missing Mortality Status
Megan Price, Emory University, United States

Using Double Robust Estimators To Provide Unbiased As-treated Effects in Randomised Trials
Richard Emsley, The University of Manchester, United Kingdom

Evaluation of Surrogate Endpoints through Direct and Indirect Causal Effects
Koji Oba, Kyoto University, Japan

Structural Mean Models for Estimating Treatment Effects in Randomized Trials with Two Active Arms
Krista Fischer, MRC Biostatistics Unit, United Kingdom

Estimation of Causal Effects for Trials of Group Administered Treatments
Chris Roberts, University of Manchester, United Kingdom

Session 5g: Poster Session 2: Epidemiological Methods
A SAS Macro for the Calculation of Relative Risks from Non-Parametric Logistic Regression Models using B-Splines
Hanno Ulmer, Innsbruck Medical University, Austria

Prevalence and Consultation Behaviour of Self-Reported Rectal Bleeding by Face-to-Face Interview in an Asian Community.
Metin Basaranoglu, Selcuk University, Turkey

The Prevalence and Risk Factors associated with Post-infective Irritable Bowel Syndrome (PI-IBS) Developed in Hospitalized Patients due to Acute Bacterial Gastroenteritis
Metin Basaranoglu, Selcuk University, Turkey

Epidemiologic Features of Nonalcoholic Fatty Liver
Metin Basaranoglu, Selcuk University, Turkey

Directed Acyclic Graphs for Phenotypes and Genotypes Association between Oral Mucosa and Rat Submandibular Gland Tumorogenesis
Mabel Brunotto, Universidad Nacional de Cordoba, Argentina

Research Ethics in the English Speaking Caribbean – the Role of the Biostatistician
Donald Simeon, Caribbean Health Research Council, Trinidad And Tobago

Propagating Imprecision: Combining Confidence Intervals from Independent Sources
Robert Newcombe, Cardiff University, United Kingdom

Alternative Graphs for Diagnostic Tests: The Agreement Chart and the Receiver Operating Characteristic (ROC) Curve
Shrikant Bangdiwala, University of North Carolina, United States

Defining and Identifying the Effect of Treatment on the Treated
Sara Geneletti, Imperial College London, United Kingdom

Preparation for a Historically Controlled Trial of StemEx: Comparing Logistic Regression with Propensity Score for Estimating the Treatment Effect
Liraz Olmer, Gertner Institute for Epidemiology and Health Policy Research, Israel

Evaluation of the Minimum Sample Size for Detecting SNPs Interactions with Classification Tree Models in Case-control Studies
Yolanda Benavente , Catalan Institute of Oncology, Spain

Rapid Surveillance of AIDS Mortality in South Africa
Ria Laubscher, South Medical Research Council, South Africa

Correction of Bias from Non-Random Missing Longitudinal Data Using Auxillary Data
Charles Hall, Albert Einstein College of Medicine of Yeshiva University, United States

Using Utility Skill Scores to Assess the Economic Utility of Diagnostic Tests
David Buckley, Greater Southern Area Health Service, Australia

Statistical Issues in Sttudying the Relative Importance of Body Mass Index, Waist Circumference, Waist Hip Ratio and Waist Stature Ratio to Predict Type 2 Diabetes
Narasimha Murthy Bhamidipati, National Institute of Epidemiology, India

Extreme Value Theory Applied to Epidemic Data: On the Estimation of Return Values for Major Epidemics
Hans Wackernagel, Ecole des Mines de Paris, France

A New Spatial Agregation Algorithm that Improves Performance of Spatial Cluster Detection
Lasse Engbo Christiansen, Technical University of Denmark, Denmark

Comparison of Simple and Multiple Imputation Methods Applied to a Risk Model for Surgical Mortality
Luciana Nunes, UFRGS, Brazil

Evaluation of Multiple Outcomes from a Cohort of Epileptic Patients: Modeling Approaches
H.Refik Burgut, Cukurova University - Weill Cornell Medical College in Doha, Turkey

Outcome-Dependent Sampling and Its Application to Environmental Health Studies
Haibo Zhou, University of North Carolina, United States

QIC Program and Model Selectioni in GEE Analyses
James Cui, Monash University, Australia

Exploring Roads to Successful Publishing: A Face-to-Face Conversation with the Editors
Theatre M