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IBC 2008 Scientific Programme

Disclaimer: This is the Final Programme, as at 20 June 2008.

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Thursday, 17 July 2008

08:30

08:30	Session 11a: Invited Session: Experimental Design for Microarrays
	Chair: Linda Haines, University of Cape Town, South Africa
	Session Organiser: Linda Haines Practical Design Issues for Microarray Experiments Gordon Smyth, The Walter and Eliza Institute of Medical Research, Australia Efficient Designs for Two-Colour Microarray Experiments Rosemary Bailey, Queen Mary, University of London, United Kingdom Nesting and Other Replication Issues in Two-Channel Microarray Designs Ernst Wit, University of Groningen, Italy Discussant (Ralf-Dieter Hilgers) General Discussion

08:30	Session 11b: Invited Session: Recent developments in joint analysis of survival longitudinal data
	Chair: Eva Petkova, New York University, United States
	Session Organiser: Zhezhen Jin Most Powerful Tests, P-Value Statistics, and Multiple Testing: Some Recent Optimality Results Edsel Pena, University of South Carolina, United States Nonparametric Longitudinal Process with Survival Time Jimin Ding, Washington University at St.Louis, United States Semiparametric Marginalized Model for Longitudinal Data with Nonignorable Dropout Mengling Liu, School of Medicine, New York University, United States Discussant (Thomas Scheike)

08:30	Session 11c: Spatial Modelling
	Bayesian Inference for Gaussian Excursion set Generated Cox Processes with Set-marking Mari Myllymäki, University of Jyväskylä, Finland Beta Versus Log-Normal Modelling: Improving Radon Mapping Techiniques Patrick Murphy, University College Dublin, Ireland Boosting Geoadditive Regression Models Thomas Kneib, Ludwig-Maximilians-University Munich, Germany Standard Errors in Systematic Sampling Chris Glasbey, Biomathematics and Statistics Scotland, United Kingdom Linear Variance Structures for Spatial Analysis of Agricultural Field Trials Hans-Peter Piepho, Universtaet Hohenheim, Germany A System for Monitoring Egg Counts of the Dengue Disease Mosquito Paulo Ribeiro, UFPR, Brazil

08:30	Session 11d: Biometrical Methods
	Simple Test Statistic for Comparison of Predictive Values of Two Diagnostic Tests Andrzej Kosinski, Duke University, United States The H-likelihood Analysis for the Rasch Model with Many Subjects Woojoo Lee, Seoul National University, Korea, Republic Of Directional Multivariate Tests Rejecting Null and Negative Effects in all Variables Ekkehard Glimm, Novartis Pharma, Switzerland On Modelling Correlated Binary Co-morbidities Susana Conde, University of Limerick, Ireland Sensitivity Analysis for Complex Dynamic Models: A Global Sensitivity Index per Factor Matieyendou Lamboni, INRA/ParisTech, France

08:30	Session 11e: Statistical Issues in Clinical Trials
	Bayesian Approach to Paediatric Clinical Trials David Schoenfeld, Massachusetts General Hospital, United States Some Statistical Issues on Post-Termination Analysis in Sequential Clinical Trials Kai Yu, National Institute of Child Health and Human Development, United States Analysis Methods of Multiple Endpoints of Various Data Types in Comparative Clinical Trials Su Young Kim, The Catholic University of Korea, Korea, Republic Of Fitting Emax Models to Clinical Trial Dose-Response Data Simon Kirby, Pfizer, United Kingdom Operation Strategy of Phase I Trials in Cancer Naoki Ishizuka, International Medical Center of Japan, Japan Quantifying the Usefulness of PD Biomarkers in Phase 2 Screening Trials of Oncology Drugs Eric Holmgren, Genentech, United States

08:30	Session 11f: Correlated Data in Epidemiology
	An Extended Random-effects Approach to Modeling Repeated, Overdispersed Count Data Clarice Demétrio, ESALQ/USP, Brazil Joint Estimation of Sensitivities and Specificities in Multi-reader Multi-disease Diagnostic Studies Alex de Leon, University of Calgary, Canada A Comparision of Statistical Methods for the Analysis of Binary Repeated Measures Data with Additional Hierarchical Structure Elmabrok Masaoud, University of Prince Edward Island, Canada Joint Rate Models for Recurrent Event and Event Marker Data Jianwen Cai, University of North Carolina at Chapel Hill, United States A Comparison of Several Approaches for the Analysis of a Cluster Randomised Trial with Repeated Measures Bruno Pereira, CRLC Val d'Aurelle, France The Consequences of Misspecified Random Effects Distributions on Predictions of Random Effects John Neuhaus, University of California, San Francisco, United States

08:30	Session 11g: Poster Session 7: Biometry
	Agreement between Two Independent Groups of Raters Sophie Vanbelle, University of Liège, Belgium Development of a Valid and Reliable Pressure Ulcer Prevalence and Incidence Surveillance Tool Jianli Li, St. Michael's Hospital, University of Toronto, Canada Accuracy of the Gaussian Approximations to Distribution of the Wilcoxom Statistics. A Graphical Approach Carine Bellera, Institut Bergonié, Regional Comprehensive Cancer Center, France Minimum-Norm Estimation for Binormal Receiver Operating Characteristic (ROC) Curves Yuval Nov, University of Haifa, Israel A Flexible System for Fitting Non-linear Models with Latent Random Variables Hans Skaug, University of Bergen, Norway Concerning Biometrics and Psychometrics John Gower, open university, United Kingdom Maternal Mortality Estimates in Major Indian States 1997-2003: A New Approach Dilip Chandra Nath, Gauhati University, India Teaching a Health Statistics Service Course with Distance Education and Face to Face Students in a Combined Environment Kevin O'Brien, East Carolina University, United States Simulated Power of Goodness-of-fit Tests for Survey Data Mike Steele, Bond University, Australia ROC Curves' Threshold Estimation Based on Cost Function Konstantina Skaltsa, University Of Barcelona, Medicine Faculty, Spain Fingerprint Module in Security Services of Learning Management System Manuel Castro, UNED, Spain Estimating Locations of Clusters in Surveillance Caroline Jeffery, Harvard School of Public Health, United States A 3-TIER Unit Cost Analysis Njoku Ama, University of Botswana, Botswana Recognition and Classification of Dermatophytes fungi using Support Vector Machines (SVM) Ana Silvia Haedo, Facultad Ciencias Exactas y Naturales-UBA, Argentina Law Enforcement Technology for Maritime Interdiction Samuel Musa, National Defense University, United States A longitudinal Study of the Effects of Life-Domain Satisfactions on Loss of Sleep Hossein Zahed, Shahid Beheshti University, Iran, Islamic Republic Of Artificial Neural Network Based Classification Rule for Classifying Dysglycemic Asian Indians in north India Dimple Kondal, All India Institute of Medical Sciences,New Delhi, India, India Data Imputation in Switchback Designs using a Mixed Model with Correlated Errors Luis Fernando Grajales Hernandez, Universidad Nacional De Colombia, Colombia Latent Growth Modeling - An Application to Longitudinal Study of "HIV1 and HIV2" Subbakrishna Kumaraswamy, national Institute of Mental Health and Neuro Sciences, India Multivariate Multilevel Analyses of the Influence of Social Capital on Self-rated Perceptions of Health: Multivariate Response Models with Missing Data Kazue Yamaoka, National Institute of Public Health, Japan Meta-analysis and Sensitivity Analysis for Selection Bias in Multi-arm Trials Hathaikan Chootrakool, University of Newcastle, United Kingdom A Mixture of Experts Model for Rank Data Brendan Murphy, University College Dublin, Ireland Statistical Modelling of Human Gait Klaus Holst, University of Copenhagen, Denmark Evidence Synthesis Meets Criminal Justice Elizabeth Merrall, Medical Research Council, United Kingdom Aortic Valve Morphology Study by Non-Parametric Permutation Tests livio finos, Univ. Roma "Tor Vergata", Italy A New Lifetime Model Applied to Human Mortality Antonio Sanhueza, Universidad de LA Frontera, Chile Decision Criteria for the Comet Assay Validation Study Takashi Omori, Kyoto University School of Public Health, Japan Pairwise Comparisons of Treatment Groups via Eulerian Tours and Hamiltonian Decompositions Catherine Hurley, NUI Maynooth, Ireland Influence Analysis in Certain Parametric Models Inmaculada Barranco-Chamorro, University of Seville, Spain The Recurrent Imputation Method: Singular Spectrum Analysis of Time Series with Missing Values Paulo Canas Rodrigues, Agricultural University of Poznan, Poland Applying a Characterisation of the Unified Generalized Poission Distribution with Respect to the Statistical Curvature TITI OBILADE, OBAFEMI AWOLOWO UNIVERSITY ILE-IFE NIGERIA, Nigeria Reproducibility and Validity Problems Associated with Nucleic Acid Amplification Tests for Detecting Chalmydia Trachomatis Alula Hadgu, Centers for Disease Control, United States Image-Derived Estimation of Arterial Input Function From Dynamic FDG-PET Studies Jacquie Kirrane, University College Cork, Ireland Calibration and KAPPA Andrew Blance, University of Leeds, United Kingdom Meta-analysis of Controlled and Uncontrolled Studies: A Case Study and Simulation Results Magdalena Kapitan, Medical University of Graz, Austria Comparison of Some Approaches for Correcting Verification Bias Ilker Unal, Cukurova University, Turkey Agreement among Multiple Raters on an Ordinal Scale: Comparison of Measurements for Agreement Yasar Sertdemir, Cukurova University , Turkey Sample Size Calculation for Screen-Positive Designs of Screening Tests Selcen Yüksel, Ankara University, Turkey Evaluation of Different Diagnostic Strategies using Additional Information Umut Arslan, Hacettepe University, Turkey The Power of Detecting Developmental Changes in Infant Studies Daniel Stahl, King's College London, Institute of Psychiatry, United Kingdom Bayesian Non-parametric Estimation of Disease Prevalence and Diagnostic Test Characteristics in the Absence of a Gold Standard Martin Ladouceur, McGill University, Canada An Evaluation of Multi-Modal Biometric Fusion Approaches Sahand Ghorbanpour, Baha'i Institute For higher Education, Iran, Islamic Republic Of Prediction of Severity of Periodontal Disease in Pregnancy Dorota Doherty, Women and Infants Research Foundation, Australia Estimating Health Disparity Indices with Confidence Intervals from Complex Sample Surveys: The California Oral Health Needs Assessment of Children Stuart Gansky, University of California, San Francisco, United States Maximum Likelihood Deconvolution of Dynamic Contrast - MRI Data via Weighted NonLinear Least Squares Niall Fitzgerald, University College Cork, Ireland Direct Manipulation Interfaces for Learning Applied to Statistics Kathleen O'Sullivan, University College Cork, Ireland

10:15

	Coffee Break

10:45

10:45	Session 12a: Invited Session: Statistical analysis of networks
	Chair: Chris Glasbey, Biomathematics and Statistics Scotland, United Kingdom
	Session Organisers: Jean-Jacques Daudin and Chris Glasbey Uncovering Latent Structure in Valued Graphs: A Variational Approach Stéphane Robin, AgroParisTech / INRA, France A Shrinkage Entropy Approach for Inferring High-dimensional Association Networks Korbinian Strimmer, University of Leipzig, Germany Prediction in Protein-Protein Interaction Networks Gesine Reinert, University of Oxford, United Kingdom

10:45	Session 12b: Special Session: A Editor's Choice of Recent Papers in Pharmaceutical Statistics
	Session Organisers: Statisticians in the Pharmaceutical Industry (PSI) Handling Drop-out in Longitudinal Clinical Trials: A Comparison of the LOCF and MMRM Approaches Peter Lane, GlaxoSmithKline, United Kingdom Power and Sample Size when Multiple Endpoints are Considered Stephen Senn, University of Glasgow, United Kingdom PREDICT-1 (CNA106030): The First Powered, Prospective Trial of Pharmacogenetic Screening to Reduce Drug Adverse Events Sara Hughes, GlaxoSmithKline, United Kingdom

10:45	Session 12c: Epidemiological Methods III
	Confidence Interval Location Robert Newcombe, Cardiff University, United Kingdom Estimation of Adjusted NNT Measures for Time-to-event Outcomes by means of the Cox Regression Model Ralf Bender, Institute for Quality and Efficiency in Health Care, Germany Adjusting for Selection Bias in Retrospective Case Control Studies Sara Geneletti, Imperial College London, United Kingdom Efficient Outcome Dependent Sampling Designs for Longitudinal Binary Response Data Jonathan Schildcrout, Vanderbilt University, United States An Extended Age Period Cohort Model for Analyasing Breast Cancer Deaths Based on Knowledge about Underlying Biology Nobutane Hanayama, Shobi University, Japan Estimating the Prevalence of Ex-injecting Drug Use in a Population Michael Sweeting, MRC Biostatistics Unit, United Kingdom

10:45	Session 12d: Mixed and Random Effect Models I
	Heterogeneous Variances in Nonlinear Mixed Effects Models via the SAEM-MCMC Algorithm Mylene Duval, INRA SAGA, France Two Logistic Random Effects Models to Analyze Bounded Outcome Scores Inmaculada Arostegui, University of the Basque Country UPV/EHU, Spain Improved Iterative Schemes for REML Estimation of Variance Parameters in Linear Mixed Models Emma Knight, The Australian National University, Australia Hierarchical Likelihood Estimation in Non Linear Mixed Models Danaelle Jolly, ISPED, France Random Effect Models for Variable Selection Youngjo Lee, Seoul National University, Korea, Republic Of Hierarchical Likelihood Methods for Nonlinear and Generalized Linear Mixed Models with Missing Data and Measurement Errors in Covariates Maengseok Noh, Pukyong National University, Korea, Republic Of

10:45	Session 12e: Agricultural Applications
	Near-factorial Experiments in a Partial Balanced Block Design with Nested Rows and Columns for Plant Protection Research Agnieszka Lacka, Agricultural University of Poznan, Poland, Poland Shrinkage and BLUP in Plant Breeders' Trials - Pros and Cons Peter Clarke, Dept of Agriculture, Western Australia, Australia Linear Models fit to Minimum Inhibitory Concentration (MIC) Data on Anti-microbial Resistance Carl Schwarz, Simon Fraser University, Canada Almost Unbiased Estimation of Proportions in Group Testing Graham Hepworth, The University of Melbourne, Australia A Comparison of Analysis Methods for Late-stage Variety Evaluation Trials Sue Welham, Rothamsted Research, United Kingdom RSSI based Indoor Tracking in Sensor Networks using Extended Kalman Filters Frede Aakmann Tøgersen, Faculty of Agricultural Sciences, University of Aarhus, Denmark, Denmark

10:45	Session 12f: Model Uncertainty and Diagnostics
	Use of the Score Test to Detect Outliers under the Alternative Outlier Model Freedom Gumedze, University of Cape Town, South Africa Model Uncertainty in Health Economic Decision Models Christopher Jackson, Medical Research Council Biostatistics Unit, Cambridge UK, United Kingdom Effects of Ambient Air Pollution (PM2.5) on Daily Mortality in Japanese 20 Cities Ayano Takeuchi, The University of Tokyo, Japan Assessment Factors for Toxicity based Risk Assessment in the the Presence of Non-exchangeable Species Graeme Hickey, Durham University, United Kingdom Non-deletion Approach to Detect Discordant Subjects in Repeated Measurements Jungwon Mun, California State Polytechnic University at Pomona, United States Model Averaging in Quantitative Risk Assessment Harriet Namata, Hasselt University, Belgium

10:45	Session 12g: Poster Session 8: Bayesian Methods
	Methods for Estimating the Parameters of a Feccundability Model from Observations on the Time Required for Conception for a Sample of Married Women Damilola Adekanmbi, Ladoke Akintole University Of Technology, Ogbomoso, Nigeria, Nigeria Bayesian Survival Analysis for Prognostic Index Development, with many Covariates and Missing Data Malcolm Farrow, Newcastle University, United Kingdom Bayesian Estimation of the Additive Main Effects and Multiplicative Interation (AMMI) Model Jose Crossa, CIMMYT, Mexico Nutrient Balance and Use Efficiency by Soybean in a Nigeria Alfisol Vincent Aduramigba-Modupe, Institute of Agricultural Research and Training, Nigeria Estimating Abundance of Pelagic Fishes Using Gillnet Catch data in Data-Limited Fisheries: A Bayesian Approach Petra Kuhnert, CSIRO Mathematical and Information Sciences, Australia Bayesian Multi-State Models for Prediction of Diabetes Complications Shiro Tanaka, Translational Research Center, Japan A Conditional Bayesian Approach for Testing Independence in Two-Way Contingency Tables Mojtaba Ganjali, Shahid Beheshti University, Iran, Islamic Republic Of On the use of Bayesian Inference to Improve Routine Ecotoxicological Data Analysis Elise Billoir, Université Lyon 1, France Bayesian Calibration When Old and New Measurement Methods are subject to Sampling Variation Chris Theobald, Biomathematics & Statistics Scotland, United Kingdom Introducing an Integrated Approach to Community Dynamics in relation to the Niche vs. Neutral Debate Crispin Mutshinda Mwanza, University of Helsinki, Finland Hidden Markov Models For DNA Sequence Segmentation : Simulation and Evaluation Darfiana Nur, The Univeristy of Newcastle, Australia, Australia A Bayesian Methodology for On-line Detecting the Onset of Influenza Epidemics David Conesa, Universitat de Valencia, Spain Rainfall Predictive Modeling to Support Agricultural Decision Making in Fucion Upland Valentina Di Stefano, University of Florence, Italy Bayesian Semiparametric Survival Model of the BSE Epidemic and Surveillance Jukka Ranta, Finnish Food Safety Authority Evira, Finland Continual Reassessment Method Adaptively Changing the Prior Distribution Referring to Initial Cohort Observation Naoki Ishizuka, International Medical Center of Japan, Japan The Prevalence of Antibiotic Resistant E.coli in Wild Rodents in a Woodland Habitat Chris Sherlock, Lancaster University, United Kingdom Double Generalized Linear Model From a Bayesian Perspective Afranio Vieira, University of Brasilia, Brazil Predictive Probability of Success as a General Tool for Clinical Development Mauro Gasparini, Politecnico di Torino, Italy Bayesian Smoothing Of MicroArray's Copy Number Data Xavier Puig, Universitat Politecnica de Catalunya, Spain Bayessian Hierachical Models for Selecting Clinical Trial Proposals of New Targeted Drugs Valentin Navarro, Catalan Oncology Institute - L'Hospitalet, Spain Bayesian Modelling of NIR Spectra to Quantify Metals in Agricultural Soils Javier Morales, Miguel Hernández University, Spain GenoSNP: A New Genotyping Algorithm for the Infinium SNP Genotyping Platform that uses Robust Bayesian Clustering Eleni Giannoulatou, University of Oxford, United Kingdom

12:30

	Lunch

14:00

14:00	Session 13a: Invited Session: Frailty models for correlated family data
	Chair: Juni Palmgren, Karolinska Institute, Sweden
	Session Organiser: Juni Palmgren Three-state Frailty Model for Age at Onset of Dementia and Death in SwedishTwins Samuli Ripatti, Karolinska Institute, Sweden Additive Gamma Frailty Models for Genetic Linkage and Association Analysis Hongzhe Li, University of Pennsylvania, United States Using Random-effects Proportional Hazards Methods to Identify Susceptibility Loci for Complex Disorders Mariza de Andrade, Mayo Clinic, United States Discussant (Terry Therneau)

14:00	Session 13b: Special Session: Showcase of papers published in JABES
	Chair: Carl Schwarz, Simon Fraser University, Canada
	Some Recent Innovations in Capture-Recapture Modelling Ken Pollock, North Carolina State University, United States Assessing Inter-population Variation in Survival Using Mark-Recapture Data Olivier Gimenez, CNRS, France Multi-List Methods Using Incomplete Lists in Closed Populations Jason Sutherland, Dartmouth College, United States

14:00	Session 13c: Bioinformatics
	Penalized Nonlinear Canonical Correlation Analysis for Whole Genome Association Studies Sandra Waaijenborg, Academic medical center, Netherlands An Algorithm to Find Co-Regulated Gene Clusters: Important Improvements Tomasz Burzykowski, Hasselt University, Belgium A Spike and Slab Centering Distribution in Dirichlet Process Mixture Models for Gene Expression Sinae Kim, University of Michigan, United States Multiple Testing in Contingency Tables Adelaide Freitas, University of Aveiro, Portugal Combinatorial Mixtures of Multiparameter Distributions: An Application to Bivariate Data Valeria Edefonti, University Of Milan, Italy Statistical Methods for the Detection of Positive Selection using Genome Maps David Ramsey, University of Limerick, Ireland

14:00	Session 13d: Clustering and Classification
	A Hierarchical Bayes Model for Two-Way Clustering Jian Zhang, University of Kent, United Kingdom Multivariate Functional Linear Discriminant Analysis Based on Pairwise Pseudo-likelihood Modeling Combined with Spline Kristien Wouters, Hasselt University, Belgium Model-Based Clustering of Longitudinal Data Paul McNicholas, University of Guelph, Canada Classification through Reduced-Dimensional Mixture of Multivariate Gaussians Cinzia Viroli, University of Bologna, Italy Combining Information Obtained from Different Spatial Clustering Methods Rossella Miglio, University of Bologna, Italy Genotype Calls and Copy Number Analysis with the Oligo Package Benilton Carvalho, John Hopkins Bloomberg School of Public Health, United States

14:00	Session 13e: Survival Analysis I
	Cure (Split Population) Models in Parametric Survival Analysis Rebecca Shanmugam, Medical Research Council, South Africa A Measure of Explained Variation of Survival Models Janez Stare, Faculty of Medicine, University of Ljubljana, Slovenia Exploiting a Gold Standard to Compare Nonparametric Estimators of Survival in the Presence of Truncated Data Mauro Gasparini, Politecnico di Torino, Italy Non-PH Survival Modelling with Frailty and Structured Dispersion Joseph Lynch, University of Limerick, Ireland Truncated Mixture Models for Mortality and Survival up to Weaning of Calves Lucas Lopez Segovia, Universitat Politècnica de Catalunya, Spain

14:00	Session 13f: Statistics in Epidemiological Research
	The Zelterman Estimate of Population Size under Heterogeneity Dankmar Boehning, University of Reading, United Kingdom The Impact of Time-dependent Bias in Proportional Hazards Modelling Jan Beyersmann, University Hospital Freiburg, Germany Uncertainty Assessment of Net Transition Probabilities of Risk Factors in Chronic Disease Modelling Estimated from Cross Sectional Data Jan van de Kassteele, National Institute for Public Health and the Environment (RIVM), Netherlands Nonparametric Estimation of Hazard Ratios of Continuous Predicators in Multistate Models Luís Machado, University of Minho, Portugal Lung Cancer Risk Associated to Radon and Smoking amoung French Uranium Miners: Impact of the Replacement of Missing Data Sophie Jacob, IRSN, France Modelling Continuous Variables with a Spike at zero – on Issues of a Fractional plynomial based Procedure Heiko Becher, University of Heidelberg, Germany

14:00	Session 13g: Poster Session 9: Regression Methods
	Weighted Metric Scaling and Distance-based Regression in Genomic Data Carles M Cuadras, University of Barcelona, Spain Multiple Regression Methodology: The Removal of Heavy Metals through Electrodialysis Ana Lima, Polytechnical Instute of Coimbra, Portugal Model Assessment, Selection and Averaging Hsin-Cheng Huang, Academia Sinica, Taiwan, Province Of China Statistical Evaluation of Some Aspects of Pito Consumption in Navrongo, Upper East Region, Ghana and Its Health Implications. Richard Clottey Anang, University for Development Studies, Ghana Relating Variety Ranks on Criteria Rankings by Men and Women Elias Obudho, University of Nairobi, Kenya Modelling Moisture Desorption Isotherms of Macadamia Lernel Robert Forrester, Australian National University, Australia Overdispersion in Wadley's Problem: The Altham-Poisson Distribution Linda Haines, University of Cape Town, South Africa Different Appoaches for Modelling Grouped Survival Data: A Mango Tree Study Suely Giolo, UFPR, Brazil Selecting the Best Treatment for the Patient's Disease Alberto Morabito, università di milano, Italy Regression Models for Analysing Cost Data Iris Reinhard, Central Institute of Mental Health, Germany Modelling Reporting Systems Gerhard Neubauer, JOANNEUM RESEARCH, Austria Using Regression Trees to Model Mercury Concentrations in Spurdog Alberto Alvarez, NUI Galway, Ireland A SAS-macro Package for Development and Validation of Prognostic and Diagnostic Models based on the Logistic Regression Model Rainer Muche, University of Ulm, Germany Modelling the Rooting Ability of Polyscias Kikuyuensis Cuttings under Different Growing Media and Indole-3-Butyric Acid (IBA) Concentrations Using Logistic Regression Vincent Oeba, Kenya Forestry Research Institute (KEFRI), Kenya A Consistent Analysis of Granular data via the use of Composite Link Functions Clive Moncrieff, The Natural History Museum, London, United Kingdom Estimation of Seed Germination Using Piecewise Regression Model Zerihun Taddese, International Livestock Research Institute (ILRI), Ethiopia Fitting a Logistic Regression Model to Forest Biometric and Soil Data Kyriaki Kitikidou, Dimokritos University of Thrace, Greece Survival of Lung Cancer Patients in the Halluca Study: An Analysis with Failty Models Andreas Wienke, University Halle-Wittenberg, Germany Log-Burr XII Regression Models with Censored Data Edwin Moises Marcos Ortega, Universidade de São Paulo, Brazil Assessment of the Effect of Chronic Exposure to Outdoor Air Pollution in Lung Function using Three-level Hierarchical Models Venedictos Kapetanakis, St. George's, University of London, United Kingdom The Models of Lactation Curves G. Tamer Kayaalp, Çukurova University, Turkey Cost Analysis of Renal Replacement Therapies before and after Renal Transplantation in Estonia Ülle Kirsimägi, Tartu University Hospital, Estonia Sensitivity Analysis of Longitudinal Data with Non-random Dropouts using Semi-parametric Models David Todem, Michigan State university, United States Is my Banana Ripe? An Introduction to Least Squares Support Vector Machines Alan Kimber, University of Southampton, United Kingdom

15:45

	Coffee Break

16:15

16:15	Session 14a: Invited Session: Advances in dynamic regimes and sequential treatments
	Chair: Erica Moodie, McGill University, Canada
	Session Organiser: Erica Moodie Direct and Indirect Approaches to Finding Optimal Dynamic Treatment Regimes Robin Henderson, Newcastle University, United Kingdom Dynamic Maintenance Treatment of Children with Leukaemia Susanne Rosthøj, University of Copenhagen, Denmark Estimating the Causal Effect of Breastfeeding on Infant Weight Gain Robert Platt, McGill University, Canada Discussant (James Robins)

16:15	Session 14b: Microarray II
	Biomarkers for a Categorical Response Variable in early Drug Development Microarray Experiments Suzy Van Sanden, Universiteit Hasselt, Belgium Pattern Discovery and Exploration with an Application to Time Course Microarray Data Susan Wilson, Australian National University, Australia Using Baseline Gene Expression for Multi-Compound Screening in Early Drug Development Experiments Adetayo Kasim, Hasselt University, Belgium Sequential Analysis for Microarray Data based on Sensitivity and Meta-analysis Guillemette Marot, INRA, France A Structural Mixed Model to Shrink Covariance Matrices for Time-course Differential Gene Expression Studies Florence Jaffrezic, INRA, France A Robust Statistical Method for the Detection of Alternatively Spliced mRNAs from Affymetrix exon Arrays George Nicholson, University of Oxford, United Kingdom

16:15	Session 14c: Bayesian Methods
	Meta-analysis of Multinomial Outcomes when Categories are Combined Patrick FitzGerald, University of Sydney, Australia Analyzing Cancer Mortality with Missing Cause-of-Failure Ananda Sen, University of Michigan, United States An Extension of Bayesian Methods to the Change-point Problem in Regression Jason Wyse, University College Dublin, Ireland Adjusting for Unmeasured Covariates - A Bayesian Approach Nicola Fitz-Simon, UCD, Ireland A Bayesian Analysis of Correlated Interval-Censored Data Khangelani Zuma, Human Sciences Research Council, South Africa Modelling of Heterogeneous Time Trends in Bayesian Age-Period-Cohort Models Andrea Riebler, University of Zurich, Switzerland

16:15	Session 14d: Models and Methods for Ecological Research
	Comparison of Methods for Phenology Adrian Roberts, Biomathematics and Statistics Scotland, United Kingdom Age-specific Parameter Estimation from Individuals of Unknown Age in Capture-recapture Data Eleni Matechou, University of Kent, United Kingdom Bootstrapping Data with Multiple Levels of Variation Alan Welsh, The Australian National University, Australia A Bayesian Mixture Model for Estimating Inter-generation Chronic Toxicity Jonathan Rhodes, The University of Queensland, Australia Measuring Both Functional and Phylogenetic Complexity: A New Challenge for Ecologists Sandrine Pavoine, University of Oxford, United Kingdom Heterogeneity in Integrated Population Modelling Panagiotis Besbeas, Athens University of Economics and Business / University of Kent, Greece

16:15	Session 14e: Analysis of Genetic Data II
	The Power of CHI-SQUARE Type Goodness-of-fit Test Statistics for the Hardy-Weinberg Law Mike Steele, Bond University, Australia Gamma Frailty Model for Linkage Analysis with Application to Interval Censored Migraine Data Marianne Jonker, Vrije Universiteit, Amsterdam, Netherlands Support Vector Machine Adaptation to Biallelic SNP Data Manuel García-Magariños, University of Santiago de Compostela, Spain A Likelihood Model that accounts for Censoring Due to Fetal Loss can accurately test the Effects of Maternal and Fetal Genotype on the Probability of Miscarriage Colin O'Donnell, Univ Colorado Health Sci Cntr, United States The Use of Disease Propensity to Reduce Heterogeneity in Nested Genetic Association Studies of Complex Conditions Fazil Baksh, University of Reading, United Kingdom Models for Genetic Linkage and Association based on Family Data Juni Palmgren, Karolinska Institute, Sweden

16:15	Session 14f: Computational Methods
	Modelling Seasonal Effects in Irish Indoor Radon Levels Órlaith Burke, University College Dublin, Ireland Modelling Cell Generation Times Using the Tempered Stable Distribution Karen Palmer, University of Kent, United Kingdom Laplace Approximation for Linear Mixed-effect Models under Elliptically Contoured Distributions Felipe Osorio, Universidad de Valparaiso, Chile Modelling the Dynamics of Biomarkers during Primary HIV Infection taking into account the Uncertainty of Infection Date Julia Drylewicz, INSERM, U897 Epidemiology and Biostatistics Research Center, France Permutation and Rotation Tests based on Pairwise Distance Measures in High-dimensional Data Siegfried Kropf, Otto von Guericke University Magdeburg, Germany Genome-wide Association Defines More than Thirty Distinct Ssusceptibility Loci for Crohn's Disease Jeffrey Barrett, Cambridge University, United Kingdom

16:15	Session 14g: Poster Session 10: Epidemiological Research
	Comparing Multiple Treatment Effect on Remission in Schizophrenia: Marginal Structural Models might Overcome Confounding in Observational Studies David Suarez, Fundació Parc Tauli, IU-UAB, Spain Bias from Categorisation of Ccontinuous Exposures Measured with Error Mark Gilthorpe, University of leeds, United Kingdom Confidence Intervals for Current Status Data with Competing Risks Marloes Maathuis, ETH Zurich, Switzerland A Bayesian latent Variable Model for the Consistency of Symptoms Reported during Hypoglycaemia George Streftaris, Heriot-Watt University, United Kingdom Clustering on Factor Analysis Dietary Patterns: the Risk of Breast and Ovarian Cancers Valeria Edefonti, University Of Milan, Italy Hierarchical Likelihood for Longitudinal Count Data Rosemeire Fiaccone, Federal University of Bahia, Brazil A Three State Markov Model Devised to Evaluate Progression of Northern Ireland Chronic Kidney Disease Patients Andrea Rainey, Queens University Belfast, Ireland How good is the Semiparametric-efficient Estimator if the Model is nearly correct? Thomas Lumley, University of Washington, United States Comparing Ordinal Regression with Rasch Analysis in an Ophthalmic Context Frances Denny, Queen's University Belfast, Ireland Elaboration of a Standard Questionnaire for the Epidemiological Survey on Dental Trauma and Avulsion Maria Lucia Marçal Mazza Sundefeld, University of São Paulo State, Brazil Non-Compliance in Surgical Patients with Herniated Lumbar Discs: An Application of a Latent Class Model as Selection Model Johnny Marzialetti, Department of Statistical Sciences, University of Bologna, Italy Some Properties of Five Parameters Generalized Logistic Distribution and its Application to Quanta Response Data AKINLOLU ADESEYE OLOSUNDE, UNIVERSITY, Nigeria NPC Test: A New Statistical Software for Multivariate Permutation Tests livio finos, Univ. Roma "Tor Vergata", Italy The T4 Cell Count as a Marker of HIV Progression in the Absence of Any Defence Mechanism morire labeodan, university of pretoria, South Africa A Stochastic Model of the Dynamics of HIV under a Combination Therapeutic Intervention morire labeodan, university of pretoria, South Africa Nonstationary Markov Transition Models for Computing the Probability of Dementia before Death Richard Kryscio, University of Kentucky, United States A Model for Psychiatric Questionnaires with Embarrassing Items Mariana Curi, University of São Paulo, Brazil Transition Probabilities and Tests to Compare Treatments with Longitudinal Binary Data Dalton Andrade, UFSC, Brazil The Analysis of Clustered Data - A Comparison between Hierarchical Models and the Generalized Estimating Equations Approach Peter Martus, Charite, Germany Prevalence and Persistence of Salmonella in Belgian Broiler Chicken Flocks: An Identification of Risk Ractors Harriet Namata, Hasselt University, Belgium A Comparison of Methods for Correlated Binary Data Gerarda Darlington, University of Guelph, Canada Flexible ROC Regression Analysis María José Rodríguez-Álvarez, University of Santiago de Compostela, Spain Moving Window Based Method for Population Survival Estimation Tomas Pavlik, Masaryk University, Czech Republic

19:00

	Conference Dinner


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