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IBC 2008 Scientific Programme

Disclaimer: This is the Final Programme, as at 20 June 2008.

Please click on the PDF icon beside the presentation title to view abstract.

Friday, 18 July 2008

08:30

08:30	Session 15a: Invited Session: New developments in statistical ecology
	Chair: Byron Morgan, University of Kent, United Kingdom
	Session Organisers: Steve Buckland and Byron Morgan Bayesian Statistical Issues in Coral Reef Ecology Paul Blackwell, University of Sheffield, United Kingdom Non-Parametric Estimation of Survival in the Wild: Appoications in Ecology and Evolution Olivier Gimenez, CNRS, France Hierarchical Models for Spatial Capture-Recapture Data Jeffrey Royle, USGS Patuxent Wildlife Research Center, United States General Discussion

08:30	Session 15b: Invited Session: Predictive model assessment and comparison
	Chair: Leonhard Held, University of Zurich, Switzerland
	Session Organiser: Leonhard Held Proper Scoring Rules, Calibration and Sharpness: Assessing Predication for an Uncertain World Tilmann Gneiting, University of Washington, United States A Bayesian Chi-Squared Test for Goodness-of-Fit in the Presence of Censored Data Valen Johnson, University of Texas M.D. Anderson Cancer Center, United States Prequential Model Selection Methods in the Assessment of Genetic Effects on Long-term Development of Coronary Artery Disease Carlo Berzuini, Medical Research Unit Biostatistics Unit, United Kingdom

08:30	Session 15c: Experimental Design in Clinical Trials
	Do You Want Your Doctor to be an Expert? - The Expertise-based Trial Design Stephen Walter, McMaster University, Canada Design Issues arising from Therapist Variation in Psychotherapy Trials Rebecca Walwyn, King's College London, United Kingdom Estimates of Information Growth Accommodating Model Misspecification Abigail Shoben, University of Washington, United States Designing a Sequentially Randomised Study with Adherence Enhancing Interventions for the First Line Treatment of Diabetes Jozefien Buyze, Ghent University, Belgium On the Three-arm Non-inferiority Trial including Placebo with a Pre-specified Margin Eisuke Hida, National Institute of Public Health, Japan Exploring the Benefits of Adaptive Sequential Designs in Time-to-event Endpoint Settings Sarah Emerson, Stanford University, United States

08:30	Session 15d: Missing Data II
	Correction of Bias in Imputing Missing Values of Categorical Variables Ruiguang Song, Centers for Disease Control and Prevention, United States A Simple Sensitivity Assessment on the Impact of Missing Data in Longitudinal Studies with Gaussian Outcomes Owen Devine, Centers for Disease Control and Prevention, United States Stochastic EM Algorithm for Incomplete Longitudinal Data Caroline Beunckens, Center for Statistics, Hasselt University, Belgium Pattern-Mixture Models for Categorical Outcomes with Non-Monotone Missingness Ivy Jansen, Hasselt University, Belgium Marginalizing Pattern-Mixture Models for Categorical Data Subject to Monotone Missingness Cristina Sotto, University of Hasselt, Belgium Comparison of Multiple Imputation Methods in HRQoL Studies with Repeated Measurements Urko Aguirre Larracoechea, Hospital of Galdakao , Spain

08:30	Session 15e: Mixed and Random Effect Models II
	Analysis of Linear Models with Two Factors Having Both Fixed and Random Levels Peter Njuho, University of KwaZulu-Natal, South Africa Simple Methods to Improve Methods to Improve MCMC Efficiency in Random Effect Models William Browne, University of Bristol, United Kingdom Smooth-CAR Mixed Models for Spatial Count Data Maria Durban, Universidad Carlos III de Madrid, Spain A Random-Effects Functional-regression Approach for Assessing Control in the Management of Renal Anaemia Robert M West, University of Leeds, United Kingdom Random Effects Ordinal/Discrete Time Models: Application to Grouped Toxicological Data Marie-Jose Martinez, National University of Ireland, Galway, Ireland

08:30	Session 15f: Statistics in Medical Research III
	A Method for Survival Data with Frailty Alexandre Silva, Instituto Superior de Contabilidade e Administração de Coimbra, Portugal Separating Borrowing Information and Forming Contrasts: Nonparametric Inference for Arbitrary Functionals of Survival Kyle Rudser, University of Washington, United States Two-stage Variable Selection Methods for Predicting the Survival Time of Lung Cancer Seungyeoun Lee, Sejong University, Korea, Republic Of Comparing Methods for Assesssing Agreement in Radiological Studies with Continuous Outcome Annette Kopp-Schneider, German Cancer Research Center, Germany Three Myths relating to Survival Analysis Elena Verbitskaya, St.Petersburg Pavlov State Medical University, Russian Federation Joint Flexible Estimation of Cumulative Effects and Non-linear Dose-response Relationships for Time-varying Exposures in Survival Analyses Michal Abrahamowicz, McGill University, Canada

08:30	Session 15g: Poster Session 11: Bioinformatics, 'Omics & Microarray Data
	A Model for the Analysis of Proteolytic 18O Stable-isotope Labeled Peptides in MALDI-TOF Mass-spectra Tomasz Burzykowski, Hasselt University, Belgium Upper Sample Limits and Outliers Detection Jean-Michel NGUYEN, CHU NANTES, France Two Stage Linear Mixed Model for Protein Expression Analysis in 2D-DIGE Elmer Fernández, Catholic University of Córdoba, Argentina The Distribution of the Numbers of Significant Results in Studies with Many Hypothesis Gerhard Hommel, IMBEI, University of Mainz, Germany Nonparametric Method for Outliers Detection Jean-Michel NGUYEN, CHU NANTES, France Sample Variability in Principal Coordinates Analysis: An Application to Classifying Genotypes Using Molecular Markers J. R. Demey, Instituto de Estudios Avanzados - IDEA, Venezuela Functional Logistic Discrimination and its Application to the Proteomics Trajectory Data Yuko Araki, Kurume University, Japan Introducing a Model to Cluster Patient Survival Times Using the Coxian Phase-Type Distribution Laura Hill, Queens University Belfast, United Kingdom Detecting Copy-number Variation in Related Individuals Jeremy Silver, Copenhagen University, Denmark Identifying Biomarkers from SELDI-TOF Protein Profiles: An Integrative Approach Yaping Cheng, University of Leeds , United Kingdom Visualizing Microarray Data Using Two Variants of Parallel Coordinate Plot Mira Park, Eulji University, Korea, Republic Of Data Quality Checking in Highly Replicated 2-dye Microarray Data Sets Andrew Mead, University of Warwick, United Kingdom Graphical Exploration of Gene Expression Data using Canonical Projection Methods and GE-Bipilots Cameron Hurst, Queensland University of Technology, Australia Cluster Analysis of Time-Course Microarray Data using Transformation Mira Park, Eulji University, Korea, Republic Of A Two stage Procedure for Identification of Molecular Markers and Stepwise Testing for the Partial Contributions SRIDHARA HEBBAGODI, Thrombosis Research Institute, India Measurement Scale Categorization according to the Measurement Error. A Gene Reduction Approach to the Mircoarray Data Analysis Yoichi Ito, The University of Tokyo, School of Public Health, Japan Covariance Models for MEG Brain Signals Fetsje Bijma, VU University, Netherlands Best Subset Selection Algorithm for Classification with Buit-in Cross-validation Victor Moreno, Catalan Institute of Oncology, Spain Estimating Recombination Breakpoint Locations Using Hidden Markov Models and Reversible Jump MCMC Alex Webb, University of Oxford, United Kingdom On the Frequency Distribution of Amino-acids Composing a Gene Anna Bartkowiak, Wroclaw University, Poland Identification of Colorectal Cancer Biomarkers from MALDI-TOF Data Elisabet Guinó, Catalan Institut of Oncology, Spain An Equivalence Approach to Global Testing of Gene Sets based on Functional Profiles Alex Sánchez, University of Barcelona, Spain

10:15

	Coffee Break

10:45

10:45	Session 16a: Invited Session: Two-phase study protocols in epidemiology
	Chair: Pascal Wild, INRS, France
	Session Organiser: Pascal Wild Two-Phase in Practice. Robustness and Planning Issues Walter Schill, University of Bremen, Germany Using the Whole Cohort in the Analysis of Case-Control and Case-Cohort Data Norman Breslow, University of Washington, United States Estimating Equation Methods for Two-phase Studies Chris Wild, University of Auckland, New Zealand Discussant (James Hanley) General Conclusions (Pascal Wild)

10:45	Session 16b: Special Session: Showcase for Biometry in South America, hosts for IBC 2010 Theatre L
	Chair: Paulo Ribeiro, UFPR, Brazil
	Session Organisers: Brazillian and Argentinean Regions of the IBS Marginal Correlation from an Extended Random-effects Model for Repeated and Overdispersed Counts Clarice Demétrio, ESALQ/USP, Brazil Paper from Argentinean Region (Author and Title to be confirmed) Discussant (Raul Macchiavelli)

10:45	Session 16c: Markov and Semi-Markov Models
	A Multistate Approach for Estimating the Incidence of Human Immunodeficiency Virus by using HIV and AIDS French Surveillance Data Cécile Sommen, INSERM U897, France A Bayesian Illness-death Model: Life Expectancies with and without Dementia for Iindividuals with Parkinson's Disease Ardo van den Hout, MRC Biostatistics Unit, United Kingdom Saddlepoint Approximation for Semi-Markov Process with Application to a Cardiovascular Randomised Study (LIPID) Serigne Lo, The George Institue / Macquarie University, Australia Use of a Hidden Semi-Markov Model for Recurrent Events Theodoros Economou, University of Exeter, United Kingdom A Multi-state Model with Flexible Type Specific Covariates Giovanni Parrinello, University of Brescia, Italy Non-Gaussian Bifurcating Autoregressive Models Martin Ridout, University of Kent, United Kingdom

10:45	Session 16d: Non- and Semi-Parametric Methods in Clinical Trials
	Semiparametric Estimation with Correlated Recurrent Event Data under Informative Monitoring Akim Adekpedjou, University of Missouri-Rolla, United States A Revisit of Robust Inference in the Cox Model Sally Galbraith, The University of New South Wales, Australia Exact Two-sample Tests for Equivalence based on Linear Rank Statistics Stefan Wellek, CIMH Mannheim/University of Heidelberg, Germany Multiple Comparison Procedures based on Permutation Tests Aldo Solari, University of Padova, Italy An Overview on Assessing Agreement with Continuous Measurements Huiman Barnhart, Duke Clinical Reearch Institute, United States

10:45	Session 16e: Time Series Analysis
	Seasonal Models of Disease that are Non-sinusoidal and Non-stationarity Adrian Barnett, Queensland University of Technology, Australia Modelling Animal Motivation by Means of a Latent-state Model with Feedback Iain MacDonald, University of Cape Town, South Africa Modeling Non-stationary Long Memory with Time Varying Spectra Nan-Jung Hsu, Institute of Statistics, National Tsing-Hua university, Taiwan, Province Of China A Generalized Autoregressive Conditional Heteroscedasticity Model (GARCH) to Analyze Continuous Blood Glucose Monitoring Data for Diabetic Patients Sanjoy Paul, University of Oxford, United Kingdom Development of Switching State Models for Bird Count Series Hitoho Takahashi, Jiyu Gakuen College, Japan Associations between Air Pollution and Doctors’ House Visits for Cardiorespiratory Diseases in Bordeaux, France: a Time-Series Analysis. Sophie Larrieu, Institute of Public Health Surveillance, France

10:45	Session 16f: Poster Session 12: Genetics
	A General Principle for the Identification of Causal Genetic Effects in Association Studies Christoph Lange, Harvard School of Public Health, United States Bayesian Genetic Mapping Emilio Carbonell, IVIA, Spain Nonparametric Multivariate Test for Genetic Linkage Soo Kim, The Catholic University of Korea, Korea, Republic Of Bias and Inflated Variance in the Genehunter Nonparametric Linkage Test Statistic Eun Kyeong Choi, The Catholic University of Korea , Korea, Republic Of Non-Parametric Modelling of Multivariate Genetic Distances in the Analysis of Spatial Population Structure at Fine Scale Cecilia Bruno, Universidad Nacional de Córdoba, Argentina Rank Transformation in Haseman-Elston Regression using Scores for Location-scale Alternatives Daniel Gerhard, Leibniz University of Hanover, Germany Tolerance Intervals from Probe-specific Mixed-models to Detect Changes in Copy Number using Multiplex Ligation-dependent Probe Amplification (MLPA) Juan Gonzalez, Center for Reseach in Environmental Epidemiology (CREAL), Spain On the Inadmissibility of Watterson's Estimator Andreas Futschik, University of Vienna, Austria Random Coefficient Regression Models in QTL Interval Mapping Alejandra Teresita Arroyo, CONICET, Argentina Analysis of Array CGH Data for the Detection of Single-cell Chromosomal Imbalances Michèle Ampe, Katholieke Universiteit Leuven, Belgium Sib Transmission and Disequilibrium Tests for Linkage and/or Association Using Multiple Highly Linked Markers Jinheum Kim, University of Suwon, Korea, Republic Of Pleiotropic Effects in Thrombotic-Related Traits Using Bivariate Variance Components Models Alfonso Buil, Institut de Recerca Hospital de Sant Pau, Spain Exploiting Epidemiological Findings when Assessing Biological Disease Markers using Pedigree Datasets Sabine Landau, Institute of Psychiatry, King's College London, United Kingdom Detecting DNA Copy Number Changes in Array-CGH Experiment Data Using CUSUM and Its Derivative Byung-Soo Kim, Yonsei University, Korea, Republic Of Heritability and Covariate Effects in a Brazilian Families Study Júlia Maria Pavan Soler, University of São Paulo, Brazil Modeling Correlated Data from a Study of Brazilian Families Júlia Maria Pavan Soler, University of São Paulo, Brazil Local Influence in Pedigree Data Felipe Osorio, Universidad de Valparaiso, Chile Power of Single Nucleotide Polymorphisms in Forensic Identification Hyo Jung Lee, Korea University, Korea, Democratic People's Republic Of A Comparison of Two Graphical Methods for Quantitative Evaluation of the Progression of Chronic Diseases Suzi Camey, UFRGS, Brazil Partial-Least-Squares-Regression Models for Genome-wide Association Studies Garrett Hellenthal, University of Oxford, United Kingdom A Bayesian Model in Genetic Association Studies Georgia Escaramis-Babiano, CIBER en Epidemiología y Salud Pública, Spain Score Tests for Genome-wide Association Studies Adjusting for Population Structure and Cryptic Relationships William Astle, Imperial College London, United Kingdom

12:30

12:30	Closing Plenary 17a: Closing Session Lecture Theatre L
	Chair: Andrew Mead, University of Warwick, United Kingdom
	Closing Comments and Acknowledgements (Andrew Mead and Tom Louis) Presentation of Awards for the Best Student Oral Presentations Presentation of Awards for the Best Poster Presentations Presentation of Awards for the Best Papers by SCC delegates from each continent Presentation about IBC Floripa 2010 (Dalton Andrade)

13:30

	Lunch and Depart


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